Egypt will be holding a first training camp this Wednesday, with a friendly scheduled for December 10th against Nigeria.
However, with AFCON not kicking off until December 21st, Slot insists Salah will not leave Merseyside until less than a week from the tournament's kickoff.
Ahead of tomorrow's clash with Sunderland at Anfield, Slot was initially asked about his star striker's emotions after benching him for the win at West Ham on Sunday.
He said: "Fair assumption and normal reaction (being upset) for someone who can play for us.
"Of course, a player isn't happy he isn't playing, he wasn't the only one I can tell you.
"The way he behaved was as you would expect from the professional he is, he was very supportive for his teammates and handled himself really well.
"You can't play that well every three days if you go with your emotions, but Mo is so disciplined. He will always be that top professional as he was the last few days."
Asked when he expects Salah to leave and join Egypt's squad, Slot replied: "He'll go on December 15th.
"The way we have worked is that there's a communication between all three - the player, the club and country. That's nothing new. But FIFA have said December 15th is last day a player has to be released."
On withdrawing Salah from the frontline, Slot also stated: "Fortunately the time I have been here he has been a superhuman being, but all players around the world there are times at a club where you are human.
"He's scored so many goals for us and I'm sure he will in the future."
Rotations
Meanwhile, asked about rotating through his XI ahead of facing Sunderland, Slot admits his selection will be dictated by the fitness of those players who played at West Ham.
He continued: "I haven't felt so much about that as yesterday we had recovery then we'll train today so let's see how players feel.
"Florian (Wirtz) has missed out one and a half, two weeks of training. For him to play so many minutes was already a good thing. It was encouraging to see him play that well, although not the first time for us - maybe the first time a lot of people noticed.
"Also positive for Alex (Isak) to score his first goal, he couldn't play 5-10 more minutes as he already felt a bit of cramp.
"He's another player who we have to see how he does."
Impressive Sunderland
Slot expects to face a competitive Sunderland, which will arrive at Anfield on the back of victory over Bournemouth.
Sunderland sit in sixth place on the Premier League table, two places ahead of champions Liverpool.
Slot said: "A big compliment for their manager (Regis Le Bris) as they brought in a lot of good players.
"I saw the game Chelsea v Arsenal on way home, two teams working so hard and fighting. Then I was aware of the fact Sunderland beat Chelsea away and drew with Arsenal.
"You can look at the league table to know they're doing well, but those two results show it.
"They are resilient. They have shown great mentality but the style they play and risks they take when not having ball, very high-paced game and players work so hard to get a result.
"A very hard-working team with a very clear identity."
He also stated: "Sunderland are either pressing really high or 11 players defend the box with all they have. That's why they are so difficult to play against.
"It's important to start a game well even without scoring a goal. We have to try that better than recently because recently apart from West Ham we've conceded."
Social media abuse
Before concluding this morning, Slot was asked about a report showing he was the most abused manager on social media in the Premier League.
The Dutchman, however, shrugged: "Maybe I expected a bit more after the Forest game!
"Abuse is never a good thing. But I am not a social media person but I'm not stupid, I'm aware of it. If you start to lose you're aware people aren't happy with you.
"What I notice and feel is the support the fans give me in the stadium. Even at 0-0 (at West Ham) the fans were singing for the team and for me."