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Mission impossible?
Despite heading into the tie in confident spirits, Manchester City suffered a sobering 3-0 defeat in the Spanish capital last week. Real Madrid once again demonstrated their immense Champions League pedigree by sweeping the visitors aside in an exhilarating first half, before comfortably defending their lead after the interval.
Can City bounce back or will Madrid cruise through? Here are our predictions for Tuesday's second leg.
Manchester City v Real Madrid: Predictions
Match Result - Manchester City: 1/2 (bet365)
Manchester City Goals Range 2-5: 1/2 (bet365)
Odds valid at the time of publication and may change.
City to win
This month's disappointing 2-2 draw with Nottingham Forest ended City's impressive run of seven consecutive home victories, a sequence of results which followed three triumphs at the Etihad during the Champions League's opening phase.
Meanwhile, Real Madrid have lost two of their first five European away fixtures this term, with one of these defeats coming at Anfield in early November. As they simply must beat their opponents to have any hope of remaining in the competition, the hosts are expected to win on the night. However, it's unlikely they'll manage to overturn a 3-0 aggregate scoreline.
Prediction: Match Result - Manchester City: 1/2 (bet365)
Explanation: This bet lands if Manchester City win the match, regardless of the final score/outcome of the tie.
Goals galore!
The stats suggest that we'll see plenty of goals on Tuesday night. Remarkably, ten of the most recent twelve contests between these teams have produced three or more goals, while the same could be said of four of City's last five outings at the Etihad.
Real Madrid have netted three or more times in eight (out of eleven) European fixtures this term, something that has also happened in six of their last eight matches across all competitions.

Prediction: Over 2.5 Goals: 4/9 (bet365)
Explanation: This bet lands if the match witnesses a total of three or more goals.
City to score between two and five goals
This may feel like somewhat of a risky bet, but Manchester City's urgent need for goals will compel them to stream forward at every opportunity. Furthermore, the Citizens have netted between two and five times in 11 of their last 13 clashes, a goals range that was also witnessed in each of their seven most recent home fixtures.
The Premier League outfit have also scored between two and five goals in four of Real Madrid’s last five visits to the Etihad.
Prediction: Manchester City Goals Range 2-5: 1/2 (bet365)
Explanation: This bet lands if Manchester City score exactly two, three, four, or five goals.
Manchester City v Real Madrid - Match Result odds
Odds valid at the time of publication and may change.
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Odds valid at the time of publication and may change.
