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The Blaugrana are currently in the midst of a busy fixture schedule, but can at least look forward to a five-day rest following this season's second visit to St. James' Park. Meanwhile, Newcastle have been struggling to build momentum in recent weeks, as their inconsistent run of form continues. The Geordies thrashed Azerbaijani outfit Qarabağ FK in their previous European tie, but have already lost five times in the Premier League since the turn of the year.
Check out our predictions for Tuesday's keenly anticipated match-up below.
Newcastle United v Barcelona: Predictions
Both Teams to Score (BTTS): 4/9 (bet365)
Barcelone to score in the second half: 1/2 (bet365)
Odds valid at the time of publication and may change.
Goals galore
All eight of Barcelona's matches in this season's Champions League have produced at least three goals, while no team other team in the competition has been involved in as many high-scoring affairs (an average of 4.5 goals per match).
The Magpies have also helped to provide plenty of entertainment, with eight of their ten Champions League contests witnessing at least three goals. In fact, the same could be said about each of Newcastle's last 12 clashes across all competitions, and indeed 13 of their most recent 16 outings at St. James' Park.
It's worth noting that there was also more than two goals in last September's meeting between these two sides, so don't be surprised if we see the same outcome on Tuesday night.
Prediction: Over 2.5 Goals: 1/2 (bet365)
Explanation: This bet will land if there are three or more goals in the match, regardless of the final result.
Both teams to score
Although they haven't managed to register a single clean sheet on Champions League duty this term, Barcelona found the net in all but one of their opening eight European fixtures - November's disappointing 3-0 away loss to Chelsea - of their opening eight European fixtures.
Both teams have scored in each of Newcastle's most recent 15 matches across all competitions, while the same trend applies to five of the Catalans' last six away encounters. The only exception in this sequence came during Barça’s sobering Copa del Rey defeat at the Metropolitano, when a controversial offside decision denied the visitors an early second-half goal after Atléti powered into a 4-0 lead during the opening 45 minutes.
Prediction: Both Teams to Score (BTTS): 4/9 (bet365)
Explanation: This bet will land if both teams score at least one goal.
This bet wins if both teams score at least one goal.
Barcelona to score after the break
Barça have scored during the second half in six of their eight Champions League outings (the exceptions being October's 2-1 loss to Paris Saint-Germain and the aforementioned defeat at Stamford Bridge) and in 27 of their last 29 matches across all competitions. The 28-time Spanish champions have also found the net after the half-time interval in 11 of their last 12 visits to opposing grounds.
Meanwhile, Newcastle have conceded second-half goals in 11 of their most recent 15 matches on home soil.
Prediction: Barcelone to score in the second half: 1/2 (bet365)
Explanation: This bet will land if Barcelona score at least once after half-time.
Newcastle United v Barcelona: Match result odds
Odds valid at the time of publication and may change.
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Odds valid at the time of publication and may change.