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Gary O'Neil's side are out to put a chastening 5-2 defeat to Manchester United behind them, and there's no better place to do it than home, where they've already shown their teeth this season with a 2-1 win over Sunderland.
With Portman Road proving a difficult place to leave with all three points historically, Ipswich will fancy turning it into a genuine fortress this season, and a positive result here would go a long way to easing the sting of last weekend's hammering.
Liverpool, meanwhile, arrive with confidence low after a winless run stretching back six league games, leaving them in need of a response against a side who've made life uncomfortable for far more fancied opponents before.
History does favour the visitors, though, as Liverpool have never lost at Portman Road in six previous Premier League visits, and have won their last four meetings with Ipswich by an aggregate score of 17-1.
Ipswich v Liverpool, Friday, 20:00 BST
Ipswich v Liverpool tips
• Both teams to score (Yes) - 57/100 with Bet365
• Over 2.5 goals - 11/25 with Bet365
• Alexander Isak to have 1+ shots on target - 33/100 with Bet365
Odds courtesy of Bet365. Correct at the time of publication and subject to change.
Both teams to score
Ipswich have kept just one clean sheet in their last 36 Premier League games and none in their last 21, while Liverpool haven't managed a shutout in nine competitive matches and have already conceded twice in each of their opening two league fixtures this term.
Moreover, six of the newly promoted side's last seven matches at Portman Road have seen both sides get on the scoresheet, and they've scored first in each of their last five games.
With Liverpool's defence still finding its feet under a new manager, backing goals at both ends at 57/100 with Bet365 offers good value.
Tip: Both teams to score (Yes) @ 57/100
Bet explanation: This bet wins if both Ipswich Town and Liverpool score at least one goal in the match.
Over 2.5 goals
Every one of Liverpool's last eight domestic away matches has produced over 2.5 goals.
Ipswich, for their part, shipped five themselves against Manchester United last time out, and with their own attacking intent allied to a defence that's struggled to keep opponents out, goals should flow freely again here.
Throw in a Liverpool front line which has been bolstered by the addition of Bradley Barcola, and there's every reason to expect this game to open up. Over 2.5 goals at 11/25 with Bet365 fits the profile of both sides nicely.
Bet explanation: This bet wins if there are three or more goals scored in total between Ipswich Town and Liverpool.
Alexander Isak to have 1+ shots on target
Alexander Isak has been a constant threat on goal so far this season, registering at least one shot on target in both of Liverpool's opening two Premier League fixtures.
His history against Ipswich specifically makes for even more eye-catching reading with four goals in just two previous league appearances against them, including a hat-trick at Portman Road.
With Ipswich already having the leakiest defence in the top flight and Isak having attempted three or more shots in both his appearances this season, there's little reason to expect him to go quiet here. At 33/100 with Bet365, backing him for at least one shot on target looks a confident and well-supported selection.
Tip: Alexander Isak to have 1+ shots on target @ 33/100
Bet explanation: This bet wins if Alexander Isak registers at least one shot on target during the match.
Ipswich v Liverpool odds
• Ipswich - 4/1 with Bet365
• Draw - 7/2 with Bet365
• Liverpool - 11/20 with Bet365
Odds, correct at the time of publication, are subject to change.
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