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The battle for Champions League football intensifies as third place Manchester United welcome fourth place Aston Villa.
League leaders Arsenal host Everton while title chasers Manchester City are away at West Ham United.
With so much at stake, we’ve gone through the numbers and odds to pick out the best betting angles for some selected Premier League games.
Burnley v Bournemouth, Saturday, 3:00 pm
Burnley’s difficult home campaign continues to raise concerns, with the Clarets winless in their last 10 league games at Turf Moor (D3 L7). However, Scott Parker’s team still possess a threat through their attacking players, particularly Zian Flemming, who has quietly emerged as one of their most consistent performers in the final third.
Bournemouth arrive in solid form, unbeaten in their last nine Premier League games (W4 D5), though draws have been a recurring theme recently with their last three matches all finishing level.
The Cherries’ games have produced plenty of action this season – only Manchester United fixtures have seen more goals than Bournemouth’s (90). Despite their attacking intent, defensive lapses remain an issue, meaning Burnley should still be able to create opportunities.
Flemming looks the most likely player to test the goalkeeper. The Dutchman has scored in his last two Premier League appearances and has registered four shots on target across his last five games. With Burnley likely to rely on his attacking drive again here, backing him to hit the target at least once looks a strong play.
Tip: Zian Flemming to play 1+ shots on target @ 11/25 with Bet365
Bet explanation: This bet wins if Zian Flemming plays at least one shot on target against Bournemouth
Arsenal v Everton, Saturday, 5:30 pm
Arsenal head into this clash in strong form and with a dominant record in this fixture. The Gunners are unbeaten in their last six Premier League meetings with Everton (W4 D2) and have lost just once in their last 15 league matches overall.
Their attacking efficiency has been particularly impressive this season, scoring 59 goals from an expected goals total of 50 – the biggest overperformance in the Premier League.
Everton, however, arrive in decent shape themselves, winning their last two league games and scoring twice in each victory. Their away form has also been encouraging, with the Toffees winning four of their last five Premier League matches on the road.
Still, history suggests they could struggle at the Emirates, where they have won just once in their last 29 league visits.
While Everton’s defensive organisation has been solid this season, Arsenal’s attacking depth and strong home form should prove decisive.
With Mikel Arteta’s side continuing to push at the top of the table, their overall quality make them clear favourites to secure another three points.
Tip: Arsenal to win @ 33/100 with Bet365
Bet explanation: This bet wins if Arsenal beats Everton regardless of the score.
Chelsea v Newcastle, Saturday, 5:30 pm
Chelsea have historically enjoyed this fixture at Stamford Bridge, winning 11 of their last 12 Premier League home games against Newcastle.
Under Liam Rosenior, the Blues have also developed a more controlled style of play, producing more sequences of 10 or more open-play passes than any other side in the league since his appointment.
Newcastle, though, have shown they can compete in this matchup recently, avoiding defeat in five of the last seven Premier League meetings between the sides.
Eddie Howe’s team remain dangerous going forward and have scored regularly this season.
Defensively, both teams have been vulnerable of late. Chelsea have failed to keep a clean sheet in their last seven Premier League games, while Newcastle are without one in their last eight.
With attacking quality on both sides, it’s difficult to see either defence shutting the other out.
Tip: Both teams to score @ 1/2 with Bet365
Bet explanation: This bet wins if both Chelsea and Newcastle score at least a goal each.
West Ham v Manchester City, Saturday, 8:00 pm
Manchester City have completely dominated this fixture in recent years, going 20 Premier League games unbeaten against West Ham (W17 D3).
Pep Guardiola has an even more remarkable record personally, never losing any of his 19 league matches against the Hammers, which is the longest such streak any manager has had against a single opponent in the competition.
West Ham did pick up a 1-0 win over Fulham last time out and will hope to build some momentum, but history at the London Stadium offers little encouragement.
They have never beaten City there in nine Premier League attempts (D2 L7). Even when competitive, they have struggled to contain City’s attacking quality over 90 minutes.
City also arrive in strong form, losing just one of their last 17 league games. Erling Haaland has been particularly ruthless in this fixture, scoring 11 Premier League goals against West Ham, which is more than he has against any other opponent.
With Guardiola’s side consistently controlling these meetings, backing them to secure another victory looks the logical choice.
Tip: Manchester City win @ 33/50 with Bet365
Bet explanation: This bet wins if Manchester City beats West Ham regardless of the score.
Manchester United v Aston Villa, Sunday, 2:00 pm
Manchester United’s home record against Aston Villa has historically been extremely strong, with the Red Devils losing just two of their last 37 league matches against Villa at Old Trafford.
Under Michael Carrick, United have also been perfect at home in the Premier League, winning all five matches he has overseen at the ground.
Villa’s form has dipped in recent months, with Unai Emery’s side winning just three of their last 11 league games. Their results have been particularly affected when key midfielders are absent, as the trio of Boubacar Kamara, John McGinn and Youri Tielemans have proven crucial to their stability this season.
Bruno Fernandes continues to be the heartbeat of Manchester United’s attack. His goals and assists have directly earned the club 23 points this season.
The Portuguese international also enjoys facing Villa, having recorded seven goals and three assists in 13 meetings across all competitions. Given his influence in Carrick’s setup, backing him to produce another decisive moment looks an appealing bet.
Tip: Bruno Fernandes to score or assist @ 18/25 with Bet365
Bet explanation: This bet wins if Bruno Fernandes scores or assists against Aston Villa.
Liverpool v Tottenham, Sunday, 4:30 pm
Liverpool have historically dominated Tottenham at Anfield, losing just one of their last 31 home league meetings with Spurs.
The Reds are also unbeaten in their last 14 home matches against them, a run stretching back to 2011. This fixture has long been one of the Premier League’s most entertaining, producing a record 209 goals.
Tottenham’s recent form is a major concern heading into this clash. They have lost their last five league games and remain without a Premier League victory in 2026.
While Spurs have picked up the majority of their points away from home this season, their current losing streak suggests confidence is extremely low.
Given Spurs’ poor form and Liverpool’s need to close the gap on the top four, the hosts look well positioned to take all three points.
Tip: Liverpool to win @ 33/100 with Bet365
Bet explanation: This bet wins if Liverpool beats Tottenham regardless of the score
Brentford v Wolves, Monday, 8:00 pm
Brentford have enjoyed recent success against Wolves, going unbeaten in their last four league meetings (W3 D1) and beating them 5-3 in this fixture last season. The Bees were extremely strong at home earlier in the campaign as well, losing just once in their first 11 league games at the Gtech Community Stadium.
However, Wolves arrive with renewed momentum after winning their last two Premier League matches. That turnaround is significant considering they had won just once in their previous 32 league games before that run.
Rob Edwards’ side have also scored goals against tough opposition recently, including Liverpool, Aston Villa, and Arsenal.
Despite Brentford’s solid record in this fixture, Wolves’ improving attacking output suggests they can find the net again here.
With the visitors showing more confidence going forward in recent weeks, backing them to score at least once looks a sensible option.
Tip: Wolves to score @ 57/100 with Bet365
Bet explanation: This bet wins if Wolves scores at least one goal against Brentford
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The odds, correct at the time of publication, are subject to change.