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Live updates
11:53 GMT - We have just over 30 minutes to go until kick-off at the Tottenham Hotspur Stadium.
11:50 GMT - Man Utd have proudly had at least one Academy player named in their first-team squad for the past 88 years, but that was almost at risk today. Kobbie Mainoo was ruled out with a knock, but Jack Fletcher - son of Darren - comes in to replace him on the bench.
Manager Ruben Amorim told reporters that he doesn't "want to be the guy" to break the record, despite selling Marcus Rashford, Alejandro Garnacho, banishing Mainoo...
11:40 GMT - Elsewhere, Sky Sports News are reporting Middlesbrough manager Rob Edwards will not take charge of their match at home to Birmingham later.
Edwards is among the favourites to take over at managerless Wolves, who play Chelsea this evening.
11:33 GMT - Spurs make four changes to their defeat to Chelsea, with Cristian Romero, Brennan Johnson, Xavier Simons and Richarlison replacing Lucas Bergvall and Mohammed Kudus who are both injured, and Rodrigo Bentancur and Kevin Danso who drop to the bench.
Man Utd make three changes to their draw at Nottingham Forest – Noussair Mazraoui, Harry Maguire, and Patrick Dorgu come in for Benjamin Sesko, Diogo Dalot, and Leny Luc Yoro.
11:30 GMT - The team news has arrived and Man Utd have dropped Benjamin Sesko to the bench. You can see how both teams line up below:
Tottenham: Guglielmo Vicario, Djed Spence, Micky van de Ven, Cristian Romero, Pedro Porro, Pape Matar Sarr, João Palhinha, Richarlison, Xavi Simons, Brennan Johnson, Randal Kolo Muani
Man Utd: Senne Lammens, Luke Shaw, Matthijs de Ligt, Harry Maguire, Noussair Mazraoui, Bruno Fernandes, Casemiro, Amad Diallo, Patrick Dorgu, Bryan Mbeumo, Matheus Cunha
11:08 GMT - When the two sides last met in the corresponding fixture last season, Spurs won 1-0. James Maddison scored the only goal for in the 13th minute.
Spurs have got the better of Man Utd of late, and are unbeaten in the last five Premier League matches between them. United are looking for their first league win between the two clubs since October 2022, with Spurs having outscored the Red Devils with 10 goals for and four against.
10:55 GMT - While we wait for team news at the Tottenham Hotspur Stadium, you can find out which players are at risk of missing out on all the action with our handy Who's Missing guide.
10:30 GMT - Welcome along to the Football Tracker on a busy day of football in the Premier League with matches affecting both ends of the table.
In the 12:30 kick-off, Tottenham host Man Utd before Everton take on Fulham and West Ham face Burnley at 15:00, with table-topping Arsenal against Sunderland at 17:30 and basement side Wolves travelling to Chelsea from 20:00.
Stay with us for all the latest news and updates throughout the day.
