At Anfield, champions-elect Liverpool will host their closest rivals Arsenal in a much-anticipated showdown. While Liverpool hold a comfortable 13-point lead at the top, the match promises an exciting contest between the league’s top two sides.
Meanwhile, Chelsea travel to Newcastle in another pivotal encounter. With European qualification on the line, this fixture could prove decisive in the battle for a top-four finish.
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We dive into the stats, analyse the odds, and make some savvy bets as we break down the potential outcomes of selected games.
Ipswich v Brentford, Saturday, 3:00 pm

Back Brentford to maintain their strong form against Ipswich, with the Bees priced at 13/20 to secure victory on bet365. Ipswich, already relegated, have struggled significantly, managing just one win in their last 16 Premier League matches, a 2-1 triumph at Bournemouth in April. During this difficult run, the Tractor Boys have conceded two or more goals in 13 of those games.
At home, Ipswich’s woes continue, having lost 10 of their last 11 Premier League matches, including seven consecutive defeats at Portman Road - the longest home losing streak in their league history.
In contrast, Brentford have been in excellent form, winning their last three Premier League games and scoring 10 goals in that span. They also edged Ipswich 4-3 in the reverse fixture earlier this season. Given Brentford’s momentum and Ipswich’s struggles, backing the Bees to extend their winning run looks a confident and appealing choice.
Bet explanation: This bet wins if Brentford beat Ipswich regardless of the score line.
Southampton v Manchester City, Saturday, 3:00 pm

Manchester City have rediscovered their rhythm and are among the Premier League’s most in-form teams.
Under Pep Guardiola’s guidance, the side has secured victories in their last four league matches, marking their joint-longest winning streak of the season. They are also aiming to win consecutive away league games for the first time since August.
With a place in next season’s Champions League on the line and Southampton already relegated, City to win at 1/5 odds on bet365 looks like the right choice.
Tip: Manchester City to win @1/5
Bet explanation: This bet wins if Manchester City beat Southampton regardless of the score line.
Bournemouth v Aston Villa, Saturday, 5:30 pm

Bournemouth suffered a narrow 1-0 defeat at home to Aston Villa in their inaugural Premier League meeting back in August 2015.
Since then, the Cherries have remained unbeaten in their last three home games against Villa, scoring exactly two goals in each encounter (two wins and one draw). Under Andoni Iraola, Bournemouth have demonstrated this season that they can compete with the league’s top sides and currently sit eighth, vying for a European spot.
Aston Villa, meanwhile, have struggled on the road, with eight of their nine defeats coming away from home and no wins against top-eight opponents away this season (D1 L5). With Bournemouth unbeaten in their last four matches, they will be confident of avoiding defeat against Villa once again.
Tip: Bournemouth to win or draw @2/5
Bet explanation: This bet wins if Bournemouth avoid defeat against Aston Villa at home.
Newcastle v Chelsea, Sunday, 12:00 pm

Newcastle have won seven of their last 11 Premier League home games against Chelsea (D1 L3), including both matches under manager Eddie Howe. This season, the Magpies already defeated Chelsea 2-0 at St James’ Park in the EFL Cup.
Newcastle’s form over the last 20 league games has been impressive; only Liverpool (46 points) have accumulated more points than the Magpies in that period.
After a goalless draw, Chelsea have rediscovered their scoring touch, netting in each of their last four Premier League matches. In their most recent game, the Blues registered the highest expected goals total (3.13) and non-penalty expected goals (2.35) any side has achieved against Liverpool in the Premier League this season.
With both teams pushing for a win to secure their Champions League places, an attacking encounter is expected. The “both teams to score” market at 1/2 on bet365 appears to be an appealing option.
Bet explanation: This bet wins if Newcastle and Chelsea at least a goal each in the game.
Manchester United v West Ham, Saturday, 2:15 pm

Manchester United host West Ham United at Old Trafford this Sunday in a clash between two sides enduring disappointing Premier League campaigns. United sit just two points above West Ham, with both teams winless in their last six league matches.
However, the Red Devils boast a strong home record against West Ham, remaining unbeaten in their last 16 Premier League home games against the Hammers (13 wins, 3 draws), including four consecutive victories without conceding.
Despite this, United’s recent form and fatigue from midweek European fixtures leave them vulnerable. West Ham’s struggles with scoring and poor away record make a win unlikely, but with both defences showing weaknesses, the “both teams to score” market at 33/50 on bet365 appears a likely outcome.
Tip: Both teams to score @33/50
Bet explanation: This bet wins if Manchester United and West Ham at least a goal each in the game.
Tottenham v Crystal Palace, Sunday, 2:15 pm

Tottenham have won just one of their last nine Premier League matches (D2 L6), conceding in each of their last ten league games, allowing a total of 20 goals. Their home form has offered little solace this season.
Key creative player James Maddison is sidelined for the remainder of the campaign with a knee injury, while captain Son Heung-min is also out, significantly limiting Spurs’ attacking options. Defensively, they have struggled, keeping only six clean sheets and conceding 57 goals overall.
Under Oliver Glasner, Crystal Palace have found impressive form since November, losing just once in their last 11 league matches (W5, 5D). They have amassed 20 points during this run, a tally surpassed by only five teams in the division. Palace’s defensive organisation and improved attacking play have made them tough opponents, even away from home.
With Palace’s momentum and solid structure contrasting Tottenham’s injury woes and inconsistent form, the visitors have a genuine chance to claim points in North London.
Tip: Crystal Palace to win or draw @11/25
Bet explanation: This bet wins if Crystal Palace avoids defeat against Tottenham Hotspur away.
Liverpool v Arsenal, Sunday, 4:30 pm

Historically, Liverpool and Arsenal have shared a competitive rivalry. The last time Liverpool won the league in 2019/20, Arsenal beat them 2-1 after the Reds were confirmed as champions.
The last three meetings between Liverpool and Arsenal have seen both teams score and at least three goals in each game.
This makes “over 2.5 & both teams to score” a high value option at 19/20 on bet365. Arsenal’s injuries and emotional fatigue after their Champions League exit make this a tough trip to Anfield, where Liverpool have been dominant all season.
With the title already decided, tensions will be low as an open game will be expected as both teams go for bragging rights.
Tip: Over 2.5 & both teams to score@11/25
Bet explanation: This bet wins if there are at least three goals in the Liverpool vs Arsenal game and each team scores at least once.
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The odds, correct at the time of publication, are subject to change.