Tottenham are on a seven-game unbeaten run across all competitions heading into clash against Villa who are aiming for a fifth successive win in all tournaments and a third straight victory over the North London side.
Solanke is progressing well
Frank, who is yet to beat Villa manager Unai Emery, first spoke on striker Dominic Solanke who hasn't played since Tottenham's 2-0 win at Manchester City in August.
"Dom's progressed well post-surgery, he's moving forwards. The good thing is he is progressing, but he is still training on his own.
"I don't want to be too negative or get too excited. How long he takes, I don't know."
Injury updates on Muani and Bissouma
Some team news now as Frank gives a worrying update on one midfielder who picked up an injury during the international break.
"Kolo Muani has trained for two weeks with the team - he looks better and better - and he's in contention for the weekend.
"Yves Bissouma unfortunately had a situation with the national team and has a ligament issue in his ankle so he'll be out for a few weeks."
Frank excited to work with Paratici and Lange
Tottenham announced the club's new sporting directors Fabio Paratici and Johan Lange this week, and Frank revealed that he is excited to get started with the pair.
"Positive about the return of Fabio Paratici. Obviously he worked as a consultant for the club so I've met him a few times over the last few months. I'm looking forward to working together.
"I'm in no doubt we will all create a good team. I'm used to working with two sporting directors - I did so at Brentford. I think you need two sporting directors now. I think they will compliment each other well.
"I was very positive about it. It will work very well. Their abilities will compliment each other very well. It is the perfect match."
Frank desperate to turn Tottenham's home form around
Finally, the Danish head coach opened up on improving home form. Spurs have only won a measly three of their last 17 top-flight games at the Tottenham Hotspur Stadium in a shocking stat Frank wants to change.
"We would like our home to be a fortress. That is the aim. If we can make it an unbelievably difficult place to come, then the job is half done.
"This needs cohesion between the team and the fans. Every game of football goes up and down with good and bad spells so we need the fans.
"When the fans are behind the team and the stadium is rocking, it is an unbelievable place."