Who's Missing: Arsenal hopeful over Saka knock ahead of big Chelsea clash

For Spurs, their injury crisis shows no signs of easing, with as many as nine first-team players out of action ahead of their vital trip to Fulham.

Elsewhere, Newcastle will be without Bruno Guimaraes when they welcome Everton to St James' Park, Liverpool's Florian Wirtz is set to miss out for the Reds with a back injury, and Manchester City are still sweating over the fitness of Jeremy Doku as their title challenge rumbles on.

See who's missing and doubtful ahead of the next round of Premier League fixtures:

Wolves v Aston Villa

WON'T PLAY

Wolves:

Chiwome | Lacking match fitness

Krejci | Red card

Aston Villa:

Kamara | Knee injury

McGinn | Knee injury

Tielemans | Ankle injury

DOUBTFUL

Hwang Hee-Chan | Injury

Alysson | Knock

Garcia | Muscle injury

Bournemouth v Sunderland

WON'T PLAY

Bournemouth:

Kluivert | Knee injury

Soler | Injury

Sunderland:

Brobbey | Groin injury

Cirkin | Injury

Mandava | Knee injury

Mukiele | Injury

Mundle | Muscle injury

DOUBTFUL

Cook | Hamstring injury

Doak | Hamstring injury

Ta Bi | Injury

Burnley v Brentford

WON'T PLAY

Burnley:

Amdouni | Knee injury

Beyer | Thigh injury

Broja | Injury

Cullen | Knee injury

Roberts | Groin injury

Tresor Ndayishimiye | Ankle injury

Tuanzebe | Achilles tendon injury

Brentford:

Carvalho | Knee injury

Dasilva | Knee injury

Milambo | Knee injury

DOUBTFUL

Hickey | Injury

Kayode | Injury

Liverpool v West Ham

WON'T PLAY

Liverpool:

Bajcetic | Hamstring injury

Bradley | Knee injury

Endo | Injury

Isak | Broken leg

Leoni | Knee injury

Wirtz | Back injury

West Ham:

Fabianski | Back injury

Pablo | Calf injury

Potts | Red card

DOUBTFUL

Frimpong | Injury

Newcastle v Everton

WON'T PLAY

Newcastle:

Bruno Guimaraes | Muscle injury

Krafth | Knee injury

Livramento | Hamstring injury

Schar | Ankle injury

Everton:

Grealish | Foot injury

DOUBTFUL

Miley | Knee injury

Alcaraz | Injury

Leeds v Manchester City

WON'T PLAY

Leeds:

Okafor | Injury

Manchester City:

Gvardiol | Broken leg

Kovacic | Heel injury

DOUBTFUL

Alleyne | Knock

Doku | Calf injury

Brighton v Nottingham Forest

WON'T PLAY

Brighton:

Tzimas | Knee injury

Webster | Knee injury

Nottingham Forest:

Boly | Knee injury

John Victor | Knee injury

Sels | Groin injury

Wood | Knee injury

DOUBTFUL

Ayari | Shoulder injury

March | Knee injury

Fulham v Tottenham

WON'T PLAY

Fulham:

Lukic | Injury

Tottenham:

Bentancur | Muscle injury

Bergvall | Ankle injury

Davies | Ankle injury

Kudus | Muscle injury

Kulusevski | Knee injury

Maddison | Knee injury

Odobert | Knee injury

Romero | Red card

Udogie | Muscle injury

DOUBTFUL

Chukwueze | Calf injury

Kevin | Injury

Robinson | Ankle injury

Danso | Toe injury

Porro | Muscle injury

Manchester United v Crystal Palace

WON'T PLAY

Manchester United:

De Ligt | Back injury

Dorgu | Hamstring injury

Crystal Palace:

Doucoure | Knee injury

Lerma | Muscle injury

Mateta | Knee injury

Nketiah | Thigh injury

DOUBTFUL

Martinez | Calf injury

Mbeumo | Injury

Mount | Knock

Arsenal v Chelsea

WON'T PLAY

Chelsea:

Colwill | Knee injury

Cucurella | Muscle injury

Fofana | Red card

Gittens | Muscle injury

Mudryk | Suspended

Arsenal:

None

DOUBTFUL

Dowman | Ankle injury

Havertz | Muscle injury

Merino | Leg injury

Saka | Injury

White | Injury

Essugo | Injury

Estevao | Muscle injury

Jorgensen | Injury