Manchester United have been dealt a blow in defence with uncertainty over whether Diogo Dalot will play again this season after sustaining a calf injury, but who else is missing?
Dalot joins a list of United players who have been sidelined ahead of their Premier League trip to Bournemouth, including the likes of Lisandro Martinez, Matthijs de Ligt and Amad Diallo.
Liverpool have a near clean bill of health with Joe Gomez the only absentee as they look to clinch the title at Anfield against Tottenham, who will still be without captain Son Heung-min for Sunday's clash.
Elsewhere, right-back Malo Gusto is a fresh casualty for Chelsea's Saturday lunchtime fixture at home to Everton as the Blues look to stay in the hunt for a Champions League place.
See who's missing and who is unlikely to feature ahead of the next round of Premier League fixtures:
Chelsea v Everton
WON'T PLAY
Fofana D. D. | Knee Injury
Fofana W. | Hamstring Injury
Guiu M. | Muscle Injury
Gusto M. | Thigh Injury
Kellyman O. | Hamstring Injury
Mudryk M. | Suspended
Broja A. | Loan agreement
Calvert-Lewin D. | Muscle Injury
Lindstrom J. | Groin Injury
Mangala O. | Knee Injury
Tarkowski J. | Thigh Injury
Brighton v West Ham
WON'T PLAY
Igor | Thigh Injury
Joao Pedro | Red Card
Kadioglu F. | Toe Injury
Milner J. | Thigh Injury
Rutter G. | Ankle Injury
Steele J. | Shoulder Injury
van Hecke J. P. | Head Injury
Webster A. | Thigh Injury
Antonio M. | Inactive
Ferguson E. | Loan agreement
Summerville C. | Hamstring Injury
DOUBTFUL
Lamptey T. | Ankle Injury
Alvarez E. | Back Injury
Cresswell A. | Ankle Injury
Wan-Bissaka A. | Ankle Injury
Newcastle v Ipswich
WON'T PLAY
Hall L. | Foot Injury
Lascelles J. | Knee Injury
Burns W. | Knee Injury
Davis L. | Red Card
Hutchinson O. | Hamstring Injury
Muric A. | Shoulder Injury
Ogbene C. | Calf Injury
Phillips K. | Injury
Philogene J. | Knee Injury
Szmodics S. | Ankle Injury
DOUBTFUL
Botman S. | Knee Injury
Broadhead N. | Thigh Injury
Townsend C. | Thigh Injury
Southampton v Fulham
WON'T PLAY
Gronbaek A. | Muscle Injury
Nelson R. | Hamstring Injury
Rodrigo Muniz | Inactive
DOUBTFUL
Taylor C. | Knock
Wolves v Leicester
WON'T PLAY
Chiwome L. | Knee Injury
Gonzalez E. | Knee Injury
Johnstone S. | Injury
Kalajdzic S. | Knee Injury
Mosquera Y. | Knee Injury
Fatawu I. | Knee Injury
Mavididi S. | Muscle Injury
Souttar H. | Ankle Injury
Winks H. | Coach's decision
DOUBTFUL
Bellegarde J. | Knock
Hwang Hee-Chan | Muscle Injury
Pedro Lima | Ankle Injury
Bournemouth v Manchester United
WON'T PLAY
Christie R. | Groin Injury
Sinisterra L. | Hamstring Injury
Unal E. | Knee Injury
Dalot D. | Calf Injury
de Ligt M. | Injury
Diallo A. | Ankle Injury
Heaven A. | Ankle Injury
Martinez Li. | Knee Injury
Zirkzee J. | Hamstring Injury
Liverpool v Tottenham
WON'T PLAY
Gomez J. | Hamstring Injury
Dragusin R. | Knee Injury
Son Heung-Min | Foot Injury