The pair picked up injuries in the Gunners' 5-2 win at West Ham last week with Gabriel being taken off at half-time and Calafiori before the hour mark.
Manchester City are going to be without Nathan Ake and possibly Manuel Akanji when they travel to Crystal Palace and Tottenham have been dealt another defensive blow with Ben Davies set to miss their clash with Chelsea.
Check out all the doubts and absentees ahead of the next round of Premier League action:
Everton v Liverpool
Postponed due to bad weather.
Aston Villa v Southampton
WON'T PLAY
Ramsey J. | Hamstring Injury
Bazunu G. | Achilles Tendon Injury
Lallana A. | Thigh Injury
Larios J. | Injury
Onuachu P. | Injury
Ramsdale A. | Finger Injury
Smallbone W. | Thigh Injury
Stephens J. | Red Card
Stewart R. | Thigh Injury
DOUBTS
Onana A. | Foot Injury
Bednarek J. | Knee Injury
Brentford v Newcastle
WON'T PLAY
Dasilva J. | Knee Injury
Gustavo Nunes | Back Injury
Henry R. | Knee Injury
Hickey A. | Thigh Injury
Jensen M. | Thigh Injury
Botman S. | Knee Injury
Krafth E. | Shoulder Injury
Lascelles J. | Knee Injury
DOUBTS
Ajer K. | Foot Injury
Trippier K. | Illness
Crystal Palace v Manchester City
WON'T PLAY
Holding R. | Lacking Match Fitness
Matheus Franca | Muscle Injury
Wharton A. | Groin Injury
Ake N. | Thigh Injury
Bobb O. | Leg Injury
Foden P. | Illness
Kovacic M. | Injury
Rodri | Knee Injury
DOUBTS
Akanji M. | Injury
Stones J. | Health problems
Manchester United v Nottingham Forest
WON'T PLAY
Manchester United
Evans J. | Knock
Lindelof V. | Muscle Injury
Shaw L. | Injury
Danilo | Ankle Injury
Sangare I. | Foot Injury
DOUBTS
None
Fulham v Arsenal
WON'T PLAY
Andersen J. | Calf Injury
Cairney T. | Red Card
Nelson R. | Thigh Injury
Reed H. | Knee Injury
Tomiyasu T. | Knee Injury
White B. | Knee Injury
DOUBTS
Calafiori R. | Injury
Gabriel | Injury
Ipswich v Bournemouth
WON'T PLAY
Donacien J. | Ankle Injury
Hirst G. | Knee Injury
Ogbene C. | Calf Injury
Tuanzebe A. | Thigh Injury
Araujo J. | Thigh Injury
Scott A. | Knee Injury
Senesi M. | Thigh Injury
Sinisterra L. | Thigh Injury
DOUBTS
None
Leicester v Brighton
WON'T PLAY
Fatawu I. | Knee Injury
Opoku N. | Broken Leg
Pereira R. | Thigh Injury
Stolarczyk J. | Ankle Injury
Winks H. | Muscle Injury
Hinshelwood J. | Knee Injury
Kadioglu F. | Toe Injury
March S. | Knee Injury
Milner J. | Thigh Injury
Webster A. | Muscle Injury
DOUBTS
Veltman J. | Muscle Injury
Welbeck D. | Ankle Injury
Tottenham v Chelsea
WON'T PLAY
Bentancur R. | Suspended
Davies B. | Thigh Injury
Moore M. | Illness
Odobert W. | Thigh Injury
Richarlison | Thigh Injury
van de Ven M. | Thigh Injury
Vicario G. | Broken Ankle
Fofana W. | Muscle Injury | England
James R. | Thigh Injury | England
Kellyman O. | Muscle Injury
Mudryk M. | Illness
DOUBTS
None
West Ham v Wolves
WON'T PLAY
None
Chiwome L. | Ankle Injury
Gonzalez E. | Knee Injury
Kalajdzic S. | Knee Injury
Mosquera Y. | Knee Injury
Traore B. | Knee Injury
DOUBTS
Ings D. | Knock
Todibo J. | Groin Injury