Maguire was recalled last month for England’s friendly matches against Uruguay and Japan, marking his first appearances for the national team since 2024.
Maguire faces strong competition for a place in the squad from Ezri Konsa, Marc Guehi, John Stones and Trevoh Chalobah, but the centre-back said he is desperate to be involved in the tournament, which runs from June 11 to July 19.
"I think it would be my last World Cup," Maguire said at United's training camp in Maynooth, Ireland.
"I've been to two but I missed out on the Euros two years ago through injury, which hurt a lot.
"So, I'm desperate to go, in whatever role the manager would want me for; whether that's starting or deciding games late on.
"I still believe, even at my age, I’m arguably one of the best defenders in the world in both boxes."
Maguire recently signed a new contract with United, extending his stay at Old Trafford until 2027 with an option for a further year. He added that the club would need to recruit well in the close season to be well positioned next term.
England are in Group L with Croatia, Ghana and Panama. They will open their campaign against Croatia on June 17 in Dallas.