The European champions' hopes of an automatic place in next year's tournament in Brazil are no longer in their own hands following a 4-0 hammering by world champions Spain last week.
England face Ukraine at Everton's Hill Dickinson Stadium in Liverpool needing to better Spain's result against Iceland to take top spot in Group A3.
Any other outcome would see England heading into the play-offs to try and punch their ticket for the finals being hosted by Brazil.
"There are some tactical decisions to make because we expect different challenges," Wiegman told a pre-match press conference on Monday.
"Yes, I will make some changes. There are some players knocking on the door and I want to see them."
Wiegman added she had a fully-fit squad available.