Ireland will be out to defend their crown for a third straight year, which would be an unprecedented feat during the Six Nations era.
However, it won't be a walk in the park with England, France, Italy, Scotland and Wales all lurking, vying for championship glory.
What, when and where is the 2025 Six Nations?
The 2025 Six Nations is the 131st edition of the competition since its inception and the 26th since its expansion in 2000.
The tournament begins on Friday, January 31st and runs through to Saturday, March 15th.
Matches will be played in the country of the home side.
England: Twickenham Stadium, London
France: Stade de France, Saint-Denis
Ireland: Aviva Stadium, Dublin
Italy: Stadio Olimpico, Rome
Scotland: Murrayfield Stadium, Edinburgh
Wales: Millenium Stadium, Cardiff
Six Nations 2025 fixtures and results
Friday, January 31st
Saturday, February 1st
Saturday, February 8th
Sunday, February 9th
Saturday, February 22nd
Sunday, February 23rd
Saturday, March 8th
Sunday, March 9th
Saturday, March 15th
Where to watch the 2025 Six Nations
Television coverage of the 2025 Six Nations will be shared between broadcasters BBC and ITV in the United Kingdom.
The BBC will carry Scotland and Wales' home fixtures while ITV will pick up matches that England, France, Ireland and Italy host.
All matches will be broadcast on terrestrial channels as well as their respective online streaming services BBC iPlayer and ITVX.
How does the Six Nations work?
The Six Nations uses a league, format with each team playing each other at least once, with three matches taking place across five rounds.
Four points are awarded for a win, two for a draw and zero for a defeat, however teams are able to earn bonus points.
A team that scores four tries or more in a match will receive one bonus point and losing teams can earn one if the margin of defeat is seven points or fewer.
A team that scores four tries or more and loses the match by seven points or fewer will be awarded both bonus points.
So, a winning team can come away with four or five points and losing sides zero, one or two.
Three bonus points are awarded to a team that wins all five of their matches, known as a Grand Slam.
Who are the title favourites?
Reigning champions Ireland are attempting to defend their Six Nations title and do it for a historic third time and are expected to be in amongst it again with skipper Caelan Doris, but aren't outright favourites to do so.
Their head coach Andy Farrell is off leading the British and Irish Lions for their tour of Australia, so Ireland seem somewhat of an unknown entity under interim boss Simon Easterby.
That opens the door a little for France, who have often been Ireland's closest challengers in recent history as they look to build on last year's second-place finish.
The French have star scrum-half Antoine Dupont back following his Olympic gold-medal heroics in the summer's rugby sevens which is, of course, a massive boost.
England, led by new captain Maro Itoje, enter the tournament after a mixed set of autumn Tests but are capable of producing as are Scotland, although it may be a step too far for them too.
Who are the players to watch?
Tom Willis (England)
A superb Premiership campaign with Saracens has number eight Tom Willis in good stead to make an impression at this year's Six Nations for England.
Willis is a powerful carrier of the ball with the assets to be a threat and he'll be out to show Steve Borthwick exactly what he's about on the big stage.
Antoine Dupont (France)
The aforementioned Dupont will have plenty of eyes on him as arguably the best rugby player in the world at the moment.
The Toulouse man is one of the most rounded players in the game and his play is one of the biggest reasons why France are up there for the title.
Sam Prendergast (Ireland)
Leinster fly-half Sam Prendergast looks poised to start in the Six Nations for Ireland ahead of Munster's Jack Crowley in which he'll grab the famous number 10 shirt.
The 21-year-old impressed in recent starts for Ireland in their final two autumn international wins against Fiji and Australia.
Ross Vintcent (Italy)
A former pizza delivery driver, Ross Vintcent made a massive impact in his Six Nations debut last year.
The nippy 22-year-old, who plies his trade for the Exeter Chiefs, will be expected to provide an edge for an Italy team looking for improvement.
Tom Jordan (Scotland)
Glasgow Warriors' Tom Jordan has shown he can flex his talents at fly-half and centre and he'll be one to definitely keep an eye on if he gets a starting spot in the middle.
New Zealand-born Jordan's versatility could come in very handy for Scotland with the loss of magician Sione Tuipulotu for the tournament through injury.
Tomos Williams (Wales)
Tomos Williams has had a very strong season for Gloucester and is poised to carry some of that form over for Wales.
Wales will likely be looking to lean on the scrum-half to work a bit of magic if they are to avoid a second straight last-place finish and the Wooden Spoon.
Six Nations 2025 prize money
The 2025 Six Nations will have an estimated £17 million in prize money on offer with the winners taking home a cool £6.5 million.
Winners: £6.5m
Runners-up: £3.5m
Third place: £2.5m
Fourth place: £2m
Fifth place: £1.5m
Sixth place: £1m
An additional £1 million is on offer for any team that wins all five games to record a Grand Slam.
If a Grand Slam is not achieved, the pot is split and evenly distributed among the teams.
Six Nations history
The Six Nations is an annual rugby tournament featuring the international teams of England, France, Ireland, Italy, Scotland and Wales.
The tournament was first played 142 years ago in 1883 as the Home Nations Championship, which was comprised of England, Ireland, Scotland and Wales – the then-four home nations of the United Kingdom.
England were the inaugural champions and were also the first winners of the Triple Crown – awarded between the home nations.
In 1910, it was expanded to become the Five Nations Championship with the addition of France, who failed to win a single title.
The Home Nations came back between 1932 and 1939 due to France's withdrawal before World War II forced a six-year hiatus.
France came back in 1947 and the Five Nations returned, lasting all the way until 2000 when Italy joined the table, thus birthing the Six Nations.
Who has won the Six Nations the most?
England and Wales have both won the most with 39 titles across all iterations of the tournament. England have 29 outright wins and 10 shared and Wales have 28 outright wins with 11 shared.
Taking just the Six Nations era into account, England are the tournament's most successful team with seven titles since its 2000 expansion.
France, Ireland and Wales trail them slightly with six titles each, while Scotland and Italy have yet to taste success in its current format.
In terms of Grand Slams, both France and Wales lead the way with four apiece in the modern era.