The normally aggressive Australian Open champion, who could potentially replace Iga Swiatek at the top of the world rankings by lifting the Venus Rosewater Dish, bagged the first set with a late break playing some delightfully delicate shots at the net.
Alexandrova had eased past her Belarusian opponent in their previous two meetings but a repeat was never on the cards under bright sunshine on Court One as Sabalenka pounced early in the second set for a 4-0 lead.
Serving with power and precision, the 2021 semi-finalist tightened her grip on the match with a solid hold and closed out the contest when fast-fading 21st seed Alexandrova sent a shot long at the baseline.
Sabalenka, who has dropped only one set in the tournament so far, will face American 25th seed Madison Keys in the last eight.