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The Red Bulls are looking to revive a Champions League campaign that has stalled, and their form at the Red Bull Arena gives them every reason to believe.
City's wobble has been unexpected after a perfect start to the season. They needed penalties to get past Brighton in the League Cup in midweek, and their record in this competition is hardly convincing, with just eight wins from their last 20 Champions League games.
They did bounce back from the 4-2 loss to PSG by thrashing AEK Athens 5-1, and they sit three points ahead of Leipzig in the league phase.
Leipzig have lost two of their three Champions League games this season, both 4-1 away from home to Como and Real Madrid, but their home form is excellent.
They have won all five home games this season without conceding, scoring 19 goals in the process, and they've won ten consecutive matches at the Red Bull Arena.
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RB Leipzig vs Manchester City: Betting tips
• Both teams to score and over 2.5 goals - 61/100 with Bet365
• Over 9 corners - 18/25 with Bet365
• Erling Haaland to score - 53/100 with Bet365
Odds courtesy of Bet365. Correct at the time of publication and subject to change.
Both teams to score and over 2.5 goals
These two teams have played six times in the Champions League, and those games have produced 30 goals, an average of five per game. Only Milan against Rapid Vienna have a higher goals-per-game ratio among fixtures played five or more times in the European Cup and Champions League.
City haven't kept a clean sheet in their last six games and have been conceding plenty of chances, while Leipzig have been prolific at home.
The one concern is that Leipzig haven't scored more than once in any of their last four Champions League games, but with City's defence this vulnerable, goals at both ends look likely. At 61/100 with Bet365, this looks a sensible pick.
Tip: Both teams to score and over 2.5 goals @ 61/100
Bet explanation: This bet wins if both teams score at least once and there are three or more goals in total.
Over 9 corners
City's games have been packed with corners lately, with seven of their last eight competitive fixtures producing more than 9.5 corners.
That trend, combined with Leipzig's attacking approach at home, suggests another high count here.
Both sides will push for a result, and City's recent defensive problems are likely to see Leipzig win plenty of set pieces too. Over 9 corners at 18/25 with Bet365 fits that pattern.
Bet explanation: This bet wins if the combined number of corners taken by both teams is ten or more.
Erling Haaland to score
Haaland has a superb record against Leipzig, scoring 12 goals in eight appearances, including six in the Champions League, five of which came in City's 7-0 win in March 2023.
With Leipzig having conceded 21 goals in six Champions League games against City, more than they've shipped against any other opponent in major European competition, Haaland should have chances again.
City at this point don't look like scoring unless Haaland does, so expect the Norwegian striker to once again get multiple chances. At 53/100 with Bet365, backing him to score looks a strong pick.
Tip: Erling Haaland to score @ 53/100
Bet explanation: This bet wins if Erling Haaland scores at least one goal during the match.
RB Leipzig vs Manchester City: Betting odds
• RB Leipzig - 4/1 with Bet365
• Draw - 7/2 with Bet365
• Manchester City - 57/100 with Bet365
Odds, correct at the time of publication, are subject to change.
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